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2012;2(1):a008888

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& Abramov, A

Barrier disruption, in turn, makes bile acids and their harmful metabolites more likely to enter the systemic circulation, thereby activating metabolic and inflammation pathways in the liver and other distal organs, and promoting the progression of NAFLD/non-alcoholic steatohepatitis (NASH) and metabolic diseases, highlighting the impact of bile acids in systemic diseases (Fleishman and Kumar, 2024)

Briefly, ECs were seeded in 6-well plates at a density of 5105/well and incubated with IL-1 (100 ng/ml) for 24 h in the presence or absence of 50 M ferroptosis inhibitor ferrostatin-1 or 10 M ferroptosis activator erastin at 37C